The Alzheimer's Association is disappointed by the Centers for Medicare & Medicaid Services (CMS) decision to allow only Coverage with Evidence Development (CED) for an Alzheimer's imaging test that would improve diagnostic accuracy and certainty in challenging cases. When used in specific populations, as outlined in criteria developed by the Alzheimer's Association and the Society for Nuclear Medicine and Molecular Imaging (SNMMI), this tool has the potential to help identify amyloid in the brain, a hallmark of Alzheimer's disease, and resolve distressing medical uncertainty.