March 19, 2018 — Artificial intelligence (AI) platform provider EnvoyAI recently announced a new partnership with 16 Bit, the winner of the Radiological Society of North America’s (RSNA) Bone Age Algorithm Challenge. EnvoyAI’s platform launched in November 2017 with 14 partners and 35 algorithms.
The EnvoyAI Exchange continues to grow, adding new premium partners and algorithms with a current total of 19 partners and 46 algorithms. 16 Bit is Toronto-based and was founded by two radiologists focused on providing practical applications of advanced AI technology to solve the most pressing diagnostic imaging problems in today’s clinical environment.
Pediatric populations frequently require correlation between skeletal maturation and chronological age. A radiograph of the left hand is typically used and patients are categorized based on comparison of bony structures to reference standards. Bone age algorithms automate this comparison process and deliver assistive results to radiologists, expediting time to diagnosis. The application of artificial intelligence using the bone age use case was a major focus of the RSNA annual meeting, where 16 Bit took center stage with their algorithm providing a mean absolute difference (MAD) of 4.265 months on the competition’s test set which used an average of three pediatric radiologist interpretations and the final report as the gold-standard. Individual radiologists differed, on average, by 7.32 months from this gold-standard. These results highlight the tremendous potential for machines to assist physicians in providing more reliable care.
16 Bit’s bone age algorithm is now available through the EnvoyAI developer portal, meaning that, upon request, anyone can test the algorithm for free against their own clinical data by uploading a DICOM file. The algorithm will be made available free for research use to EnvoyAI pilot sites, which will allow for fast implementation via the EnvoyAI platform.
The 16 Bit algorithm was demonstrated at the 2018 Healthcare Information and Management Systems Society (HIMSS) annual meeting, March 5-9 in Las Vegas. EnvoyAI was an exhibitor at HIMSS, located in the booth of distribution partner TeraRecon.
For more information: www.envoyai.com
October 24, 2025 
